A new study, co-authored by UT Biochemistry and Cellular and Molecular Biology Associate Professor Nitin Jain and recent graduate Sara Lemmonds, could change the way scientists look at one of the most essential enzymes in medicine in hopes of designing better and more cost-effective drugs in the future.
Enzymes are molecules that speed up chemical reactions inside cells. The human body is home to thousands of enzymes that perform vital functions such as the digestion of fat and the breakdown of sugar into glucose.
The paper, published in Proceedings of the National Academy of Sciences, looks closely at Cytochrome P450, an enzyme that occurs naturally in the body and other environments. This enzyme is critical in metabolizing over 90 percent of all pharmaceutical drugs.
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